Medicine Overview of Amphoject Injection
Amphoject 50 mg Injection is used in the treatment of severe fungal infections and kala-azar
Side Effects of Amphoject are Headache, Injection site pain, Vomiting, Nausea, Stomach cramp, Fever, Anemia (low number of red blood cells), Heartburn, Rapid breathing.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Amphoject 50 mg Injection is an antifungal medication. It kills fungi by destroying the fungal cell membrane.
In Depth Information on Amphoject Injection
- Before you take amphotericin B, inform your doctor if you suffer from diabetes, liver/kidney problem or are on dialysis or have low potassium level in blood.
- You should monitor your condition through regular laboratory evaluation of potassium, magnesium as well as renal, hepatic and hematopoietic function.
- Take precautions as amphotericin B may reduce the ability to drive or operate machinery.
- Tell your doctor if you are or planning to become pregnant or are breastfeeding.
Amphoject Injection related warnings
Interaction with alcohol is unknown. Please consult your doctor.
Amphoject 50 mg Injection is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
Amphoject 50 mg Injection is probably unsafe to use during lactation.
Limited human data suggest that the drug could represent a significant risk to the baby.
Amphoject 50 mg Injection may cause side effects which could affect your ability to drive.
Amphoject 50 mg Injection is safe to use in patients with kidney disease. No dose adjustment of Amphoject 50 mg Injection is recommended.
However, inform your doctor if you have any underlying kidney disease.
There is limited information available on the use of Amphoject 50 mg Injection in patients with liver disease. Please consult your doctor.
If you miss a dose of Amphoject 50 mg Injection, please consult your doctor.
Frequently asked questions about Amphoject Injection
Q. Is Amphoject fungistatic or fungicidal?
Amphoject is fungicidal in nature, it acts by killing the fungus
Q. Is Amphoject light sensitive?
Amphoject is not light sensitive
Q. What is Amphoject liposomal?
Liposomal Amphoject is a lipid-associated formulation. Liposomal encapsulation or incorporation into a lipid complex of Amphoject can substantially improves drug safety especially nephrotoxicity associated with the drug
Q. Is Amphoject an antibiotic?
Yes, Amphoject is an antifungal antibiotic for the treatment of serious infections caused by fungi like fungal infections of one or more deep organs of the body, suspected fungal infections in patients with a raised temperature and neutropenia (reduced number of white blood cells [neutrophils]) and Visceral leishmaniasis (disease caused by a parasite)
Q. Is Amphoject testing dose needed?
Yes, administration of Amphoject is associated with allergy (severe and serious allergic) reaction, therefore it is recommended to administer a test dose before starting the therapy to check for sensitivity
Q. How is Amphoject administered?
Amphoject is either administered as intravenous injection or infusion by a registered medical professional only
Q. How does Amphoject cause nephrotoxicity and hyperkalemia?
Amphoject can disrupt the lipid components of human kidney cells, thereby causing nephrotoxicity. The exact mechanism of hypokalemia is not known, but kidney damage may result in excessive loss of potassium in urine.
Severely interacts with other drugs like
Taking Amphoject with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Medicines with composition Deflazacort: Ducort, Defmark, Zacdef, Ecodef, Defalone, Renze, Jeevcort, Flazassil, Exacort, Solo D
Medicines with composition Gentamicin: Begenta, Indogenta, Spagen, GB Gen, Garacin, Gentadin, Jentin, Gen, Zentax, Gentivin
Medicines with composition Methylprednisolone: Zencort-M, Welone, Rigapred, Premeth, Lumi M, Mep, Aricort M, Metcort, Ultrapred, Meprosol
Medicines with composition Prednisolone: Ranisol, Vepred, Catapred, GB Pred AC, Thiopred, Predar, Preden, Nephcorte, Sterid, Pensone
Medicines with composition Budesonide: Budojet, Budemon, Budate
Medicines with composition Hydrocortisone: Stacort, Maxicort, Geocort, Cortimet, Cortis H, Hyss, Raghucort
Medicines with composition Tacrolimus: Imunotac, Emgraf
Medicines with composition Zidovudine: Zidohope, Zivudin
Medicines with composition Dexamethasone: Dexamax, OD Dex, Adexa, Dexaril, Dexarain, Dexalide, Dexton, Dekadin, Pfidex, Dexacron
Medicines with composition Netilmicin: Netyl, Internet
Medicines with composition Vancomycin: Vistovanc, Vancocare, Vancogram, Vanolac CP, Vanlee, Helvance, Vanmax
Medicines with composition Itraconazole: Itracip, Itraspan, Itzo, Canzit, Cositra, Itoz, Belitra, Sitra, Ozitral, Itrapro
Medicines with composition Fluorometholone: FMN, Fluorobell
Medicines with composition Amikacin: Mikasun, Vizocin, Amricin, Gramika, Amitrex, Welmic, Spakin, Acean, Abiox, Blocin
Medicines with composition Neomycin: Neocin
Medicines with composition Indapamide: Excrete, Indizon, Indicard, Inklud
Medicines with composition Voriconazole: Voristil, Fungior
Medicines with composition Betamethasone: Catrisol, Betaforte, Betacon, Betalide, Becort, Betastamine, Ascort, Betachlor, Betan, Betapar
Medicines with composition Tenofovir disoproxil fumarate: Vipteno, Hepdoze
Medicines with composition Ketoconazole: Ketozoe, Ketazol, Tako, Hitoral, Furid, Ketocron, Fungidor, Fungimin
Medicines with composition Tobramycin: Bactob, Torvis, Tojawa, Cobex, Tobran, Tobaking, Obra, Tomin, Toram, Tobax
Medicines with composition Digoxin: Cardisip
Medicines with composition Fluconazole: Fungis, EF Z, Rocflu, Welcon, Fluzole, Geoflu, Rascon, Con F, Fucan, Flucur
Medicines with composition Triamcinolone: Darcort, Trilone, Mycort, Presticort-T, Tacit, Alcicort, Kapiswit
Medicines with composition Hydrochlorothiazide: Hyros
Medicines with composition Chlorthalidone: Chlornol
Medicines with composition Lamivudine: Heptavir
One of the following vendor pharmacies will deliver Amphoject 50mg Injection: PHN, JSL, TSS, TOM, UPA, QLF, TNH, BLP, ANS, NTB, SCP, KHD, MJT, SSI, 4IT, DHP, KMC, DFP, HTS, LHP, ZVP, DLY, HIP, HSP, AVS, DPL, NSL, EPS, DHR, CRN, RPP, ARD, BGS, BMJ, GFL, GHR, JVN, PRL, NXG, SWA, BSN, KNH, WHL, GLD, BNC, PRN, HAT, MLC, RDH, BHS, SHN, DLP, DGN, WPL, SBN, QTM, EMB, BBN, SGH, SAA, TFP, RPI, RKS, 1MH, ESY, CMC, BRC, ASP, VOP, RWP, OLT, RVC, SDE, AYN, KIM, MBP, SCH, OWN, SPD, GLM, PNT, HNP, PRC, HLT, PHC, HCP, FIP, MAM, HBV, NLP, PVP, DVH, NVY, MAK, KIS, VTR, HMP, SHD, JJE, ZPR, AVL, FRM, DRA, NVL, MAP, CPK, SVH, NNP, DYL, AXM, EVP, RHL, BNA, NTL, STS, BNT, EQN, NDP, MRS, LMS, JIV, RHS, 9MM, VSL, GEO, ALY, RGH, AGT, HPC, MDO, HGI, PTI, BAP, HSM, PWN, SLC, BTM, USF, VNS, KLC, AVB, RRP, HPP, CMD, GTC, NPH, PTP, HEX, HZF, VJS, UMP, MKT, BJP, LHA, PLT, PRT, NEO, AFT, DAO, VRS, SJP, AMH, ABP, NLG, DYG, OWP, PMA, MKS, ATL, GMA, TAT, BHA, SSS, JVO, IPP, PNQ, GPP, THP, EEC, MPC, SHC, MDH, AYM, UHP, RSA, PEN, SRG, PSF, WHP, SGC, SBL, SPF, MIP, XMX, TRP, UVD, AHP, BIO, IMC, ZEL, SIO, WSI, PPR, SDM, GNC, KHH, ANT, HWS, VHP, WAD, BHM, YMI, MFN, BAL, AYU, SMN, GDA, RUS, SNH, SMS, SLN, KHC, SWP, RSS, OMV, CLT, BBS, ADT, SAF, RTL, MAX, VDH, ANP, BLE, EAN, IAD, GGL, ALC, OBS, FGH, VSC, RAC, INC, RDR, MSD, GBL, BHP, SNG, DPP, SBA, AMR, DZY, JBT, IPL, NAS, JHC, STA, SVS, WDE, BDI, AAR, LCC, OHM, ATP, RHW, BJR, APS, OIP, BLS, AAY, ENP