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Amnurite P 10 mg/75 mg Tablet

Prescription Required
Storage
Store at room temperature (10-30°C)

Overview

Introduction

Amnurite P 10 mg/75 mg Tablet is a prescription medicine used in the treatment of neuropathic pain. It works by increasing the level of chemical messengers in the brain. This helps in regulating the mood and stopping the movement of pain signals from nerves to brain.

Amnurite P 10 mg/75 mg Tablet is taken by mouth with or without food. However, it is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. In case you miss a dose of this medicine, take it as soon as you remember. Try never to skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor as it may worsen your symptoms.

Some common side effects of this medicine include constipation, weight gain, sleepiness, dryness of mouth, and increased heart rate. Initially, this medicine may cause a sudden drop in the blood pressure when you change positions, so it is better to rise slowly if you have been sitting or lying down. It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain and to control it, you should exercise regularly and take a balanced diet. Remember to inform the doctor if you develop any unusual changes in the mood as this medicine may lead to suicidal thoughts.

Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Amnurite P Tablet

Side effects of Amnurite P Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Amnurite P

  • Constipation
  • Weight gain
  • Sleepiness
  • Dizziness
  • Tiredness
  • Blurred vision
  • Dryness in mouth
  • Increased heart rate
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Difficulty in urination
  • Uncoordinated body movements

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Constipation
    Try to eat foods which are high in fiber such as fresh fruits, vegetables and cereals to increase the bulk and consistency of bowel movements. Drink plenty of water or non-alcoholic drinks and stay hydrated to promote healthy digestion. Increasing physical activities such as walking, yoga and regular exercise can also be helpful. If your condition does not improve, you can ask your doctor to prescribe you laxative medicine.
  • Coping with Weight gain
    Try to eat a healthy balanced diet without increasing your portion sizes. Avoid processed meat or poultry and seafood. Eat small, frequent meals and eat slowly. Do not snack on foods that contain a lot of calories such as crisps, cakes, biscuits and sweets. If you feel hungry between meals, eat fruits and vegetables which have low calories. Avoid reaching for a sugary drink if you feel stressed. Fasting once a week can be an effective way to lose weight. Make sure you get enough sleep. With proper diet and lifestyle changes, you might not gain any weight or may gain only a small amount. Even then if it bothers you, ask your doctor if there are any alternative medicines that do not have this side effect.
  • Coping with Sleepiness
    If the medicine is making you drowsy during the day, stop what you are doing and sit or lie down until you feel better. You can also consider taking a nap. Physical exercises such as walking may be helpful. Do not drink alcohol, as it will make you feel more tired. Avoid driving or operating heavy equipment when you are feeling drowsy. This problem usually goes away as your body gets used to the medicine. However, if it does not, ask your doctor if you can take your medicine at bedtime or whether the dose can be reduced.
  • Coping with Dizziness
    This is usually short-lived and should go away within a few days. If this happens, stop what you are doing and sit or lie down until you feel better. Lying still in a dark, quiet room may help reduce the spinning feeling. Sleep with your head slightly raised on two or more pillows. Get up slowly from a lying or sitting position. Get plenty of rest and try to relax as being anxious can make it worse. Try taking this medicine at bedtime to reduce the symptoms. Drinking plenty of water and ginger tea may also help. Avoid alcohol, caffeine and smoking as it will make you feel worse. Avoid driving or using tools or machinery until you feel better.
  • Coping with Tiredness
    Make sure you rest and drink plenty of fluids. Eat a well-balanced diet to keep your energy levels up. Do not drink too much alcohol. Do not drive or use tools or machinery until you feel better. Other things that can help include doing some gentle exercise every day, prioritizing and pacing your activities and having a short nap if you need to. If you are still having problems after a week, speak to your doctor, as they may want to change you to a different type of medicine.
  • Coping with Blurred vision
    You can consider washing your eyes with water. Avoid driving or using tools or machines if your vision is impaired. Do not take your next dose if your vision is still blurry. If it gets worse or does not improve, ask your doctor to recommend eye drops or talk about changing your medications.
  • Coping with Dryness in mouth
    Keep a drink available that you can sip through the day. Rinse your mouth with warm salted water and chew sugarless gum or hard candy. Try breathing through your nose more often than your mouth. Avoid caffeinated beverages, smoking and alcohol because they can make your condition worse. Use lip balm if your lips are also dry. Try to avoid foods that are acidic (like lemons), spicy, salty or sugary. If this side effect bothers you or does not go away, talk to your doctor about artificial saliva products or other suitable treatments.
  • Coping with Increased heart rate
    Breathe in slowly through your nostrils and then breathe out through your mouth. Repeat this until you feel calm. Try sitting cross-legged and drink plenty of water. Splash cold water or apply a cold towel or ice pack on your face for 20-30 seconds. It is important to make sure that you are not taking more than the prescribed dose. As a preventive measure, you should limit the amount of alcohol you drink and give up smoking. Also, cut down the amount of coffee, tea or cola you drink. In general, being physically active and eating a healthy well-balanced diet is good advice for any heart condition. If the condition does not improve, consult your doctor as they may need to change you to a different type of medicine.
  • Coping with Difficulty in urination
    Relax when you try to pee. Don't try to force the flow of urine. If it doesn't happen, try again later. Limit drinks that increase urination such as coffee, tea and other caffeinated beverages. Continue to drink plenty of water each day. Gentle massage and hot compression on your lower abdomen can help relax your muscles and may improve your urine flow. Doing exercises that strengthen the bladder muscles such as pelvic exercise will be of help. Distract your attention by thinking about something else. Avoid alcohol and smoking because both can aggravate the condition. Talk to your doctor urgently if you can not pee at all.

How to use Amnurite P Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amnurite P 10 mg/75 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Amnurite P Tablet works

Amnurite P 10 mg/75 mg Tablet is a combination of two medicines: Amitriptyline and Pregabalin. Amitriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Together, they relieve neuropathic pain (pain from damaged nerves). Pregabalin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Amnurite P 10 mg/75 mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Amnurite P 10 mg/75 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Amnurite P 10 mg/75 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Amnurite P 10 mg/75 mg Tablet may cause side effects which could affect your ability to drive.
Amnurite P 10 mg/75 mg Tablet may impair your alertness which may affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Amnurite P 10 mg/75 mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Amnurite P 10 mg/75 mg Tablet may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Amnurite P 10 mg/75 mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Amnurite P 10 mg/75 mg Tablet may not be needed in these patients. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Amnurite P 10 mg/75 mg Tablet
₹15.93/Tablet
Neugalin A 10mg/75mg Tablet
Shasun Pharmaceuticals Ltd
₹14.7/Tablet
save 8%
Maxgalip AT Tablet
Sun Pharmaceutical Industries Ltd
₹20.7/Tablet
30% costlier
Neugatrip Tablet
Sun Pharmaceutical Industries Ltd
₹20.7/Tablet
30% costlier

Fact Box

Habit Forming
No

Patient Concerns

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I am taking amnurite p since 4 months for relief from nerves pain and anxiety. My has advised to continue with it for 2 more months. Whether, it would be safe to continue with amnurite p till my nerves pain in right thy and near tail bone is completely subsided.
Dr. Akshat Goel
Orthopaedics
It's safe continue
Fasting blood glucose 260 mg/DL P p - 330mg/DL Complaint of headache and treatment with glycomet
Dr. Sanjay Bhatt
Physician
I think medicine you are taking is not sufficient for you. Needs to make some changes in the dose of medicine you are taking. So discuss with your doctor.
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User Feedback


FAQs

Q. Is there anything I need to avoid while taking Amnurite P?

Amnurite P may impair your thinking or reactions. Be careful while driving or doing an activity that requires you to be alert. Do not drink alcohol while taking Amnurite P. It can increase the effects of alcohol, which could be dangerous. Grapefruit and grapefruit juice may also interact with this medicine and cause unwanted side effects. Avoid exposure to sunlight or tanning beds. Use of Amnurite P can make you more prone to sunburns. Wear protective clothing and use sunscreen when you are outdoors during daytime.

Q. How often should I see the doctor?

You may need to see your doctor regularly if you have started taking Amnurite P. However, you must consult your doctor if the recommended doses do not relieve your symptoms or you experience some unwanted side effects that affect your routine activities.

Q. What are the instructions for the storage and disposal of Amnurite P?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. What is Amnurite P?

Amnurite P is a combination of two medicines: Pregabalin and Amitriptyline. This medicine is useful in the treatment of nerve pain (neuropathic pain). This medicine calms the damaged or overactive nerves by acting on the patient's brain, thereby decreasing the pain sensation.

Q. Can I stop taking Amnurite P when my pain is relieved?

No, you should not stop taking Amnurite P even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Amnurite P, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain and sweating. You may need to gradually taper the dose before you stop the medication completely.

Q. How to manage weight gain associated with the use of Amnurite P?

Amnurite P can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight. However, preventing weight gain is easier than losing increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). Do not eat foods that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits, and sweets. If you feel hungry between meals, avoid eating junk food and eat fruits, vegetables and low-calorie foods. Regular exercise will also help prevent weight gain. If you keep good eating habits and exercise regularly, you might not gain any weight.

Q. Can the use of Amnurite P cause sleepiness or drowsiness?

Yes, Amnurite P may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities at the beginning of your treatment until you know how the medicine affects you. Inform your doctor if you experience such episodes while taking this medicine.

Q. Can the use of Amnurite P affect my sex life?

The use of Amnurite P can affect the sexual life of both men and women. Different sexual problems can occur due to Amnurite P like decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort during intercourse. If you experience these problems, discuss with your doctor but do not stop taking Amnurite P.

Q. Can the use of Amnurite P change the color of urine?

Yes, Amnurite P can change the color of the urine to blue or green. This change of color is expected while using Amnurite P, and it is not harmful. Your urine color becomes normal once you stop taking Amnurite P.

Q. Are there any serious side effects associated with the use of Amnurite P?

Serious side effects with Amnurite P are uncommon and rare. Tell your doctor as soon as possible if you notice changes in body temperature, difficulty in breathing, increased heartbeat (palpitations), weakness, unsteadiness when walking, reduced coordination or slowed reactions, unusual changes in mood or behavior such as restlessness, nervousness, or excitement, signs of depression, seeing or hearing things that are not there, irrational thinking, blurred or double vision, uncontrollable jerky eye movements, difficulty seeing, signs of frequent infections such as fever, severe chills, sore throat or mouth ulcers. These side effects are uncommon but may be serious and may need urgent medical attention.

Q. How long will Amnurite P take to act?

An initial benefit with Amnurite P may be seen after 2 weeks of treatment. However, it may take around 2-3 months to see full benefit. It may even take longer in some patients.

Q. What if I forget to take Amnurite P?

If you forget to take the scheduled dose of Amnurite P and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effect due to overdosage. If you are not sure what to do, ask your doctor about taking Amnurite P.

Q. What if I take too much of this drug by mistake?

In a situation like this, contact your doctor immediately or seek emergency help at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Symptoms of an overdose may include drowsiness, weakness, unsteady when walking, having double visions, slurred speech or diarrhea, confusion, blurred vision, dizziness, body temperature changes (low and high), difficulty in breathing and increased heart beat.

Q. Will a higher than the recommended dose of Amnurite P be more effective?

No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms, that are not relieved by the recommended doses, please consult your doctor for re-evaluation.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Centaur Pharma. Amitriptyline+Pregabalin. [Accessed 22 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

709, 7th Floor, Palm Spring Center, Link Road, Malad West, Mumbai- 400064
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