Aminophylline is used to relieve bronchospasm (constriction of airways) and difficulty in breathing associated with asthma or chronic obstructive pulmonary disease (COPD). It is also used in heart failure (inability of heart to pump the blood) and apnea (temporary cessation of breathing especially during sleep) in premature infants.
How it works
Aminophylline, a xanthine derivative, is a complex of theophylline and ethylenediamine. Theophylline acts through many ways including action on phosphodiesterase enzyme and adenosine to expand the air passages of the lungs, which helps relieve chest tightness and wheezing (bronchospasm) causing relaxation of smooth muscle of the bronchial airways. It also has stimulant effect on respiration.
Common side effects
visual disturbances, feeling faint or dizzy, restlessness, abnormal levels of electrolytes in your blood, Hypersensitivity reactions with difficulty in breathing, feeling of dizziness or spinning, tummy pain, swelling of the eyelids, extreme thirst, heartburn, dyspepsia, signs of skin allergy such as a rash, not being able to sleep tremors, thumping heart beat or a change in your normal heart beat, itching or redness of skin and pain at the site of the injection., excited behavior, confusion, face or lips, diarrhea, fever, rash or itching ; feeling sick or being sick, fits, feeling anxious, headache, gastrointestinal bleeding