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Composition for AMDEPIN H

Amlodipine(5 mg),Hydrochlorothiazide(12.5 mg)

food interaction for AMDEPIN H

alcohol interaction for AMDEPIN H

pregnancy interaction for AMDEPIN H

lactation interaction for AMDEPIN H

Avoid Amdepin h 5 mg/12.5 mg tablet with grapefruit juice.
Taking Hydrochlorothiazide with alcohol may have additive effects in lowering blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.
Amdepin h 5 mg/12.5 mg tablet may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Amlodipine(5 mg)


Amlodipine is used to treat high blood pressure (hypertension) and severe pain in chest.

How it works

Amlodipine belongs to a class of drugs called calcium channel blocker. It reduces the amount of calcium that enters the smooth muscles of the blood vessels and heart. As muscle cells require calcium to contract, reducing the flow of calcium causes the muscle cells to relax and blood vessels to dilate, reducing blood pressure, force and rate of the heartbeat. It improves blood and oxygen supply to the heart muscles.

Common side effects

Palpitations, Abdominal pain, Chest pain, Dizziness, Drowsiness, Fainting, Fatigue, Flushing, Headache, Lightheadedness, Limb swelling, Stomach upset
Hydrochlorothiazide(12.5 mg)


Hydrochlorothiazide is used to treat high blood pressure (hypertension). It also treats fluid retention (edema) due to congestive heart failure or cirrhosis of liver or kidney disorder.

How it works

Hydrochlorothiazide belongs to class of medications called thiazide diuretics. It acts by eliminating the fluid and salts from the body. It works on the kidneys to produce more urine which removes extra water and certain salts from the body which in turn lowers blood pressure and swelling.

Common side effects

Increased sensitivity to light, Excessive thirst, Abnormal heart rhythm, Skin rash, Allergic reaction, Altered blood lipids, Convulsion, Drowsiness, Dry mouth, Electrolyte imbalance, Vomiting, Gastrointestinal disorder, Gout, Headache, Increased glucose level in blood, Increased uric acid level in blood, Decreased potassium level in blood, Decreased magnesium level in blood, Decreased sodium level in blood, Decreased blood pressure, Lethargy, Muscle pain, Weakness


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Expert advice for AMDEPIN H

Take the appropriate dose of amlodipine with any liquid, with or without food at any fixed time each day.
Do not drive if you experience side effects like dizziness, sleepiness or blurred vision on taking amlodipine.
Check your blood pressure one week after starting this drug and conuslt your doctor if it has not improved.
It can cause ankle or foot swelling. Consult your doctor if it it doesn't improve over time.
Do not start or continue amlodipine tablets and consult your doctor:
  • If you are allergic (hypersensitive) to amlodipine or any of its other ingredients.
  • If you are pregnant or planning to become pregnant or breast feeding.

Frequently asked questions for AMDEPIN H


Q. Is amlodipine safe?
Amlodipine is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is amlodipine a diuretic/ blood thinner/ beta-blocker/ statin/ ACE inhibitor or a nitrate?
Amlodipine is a calcium channel blocker, not a diuretic, blood thinner, beta-blocker, statin, ACE inhibitor or a nitrate.
Q. Can I take amlodipine with Viagra?
Amlodipine does not have any significant interaction with sildenafil, the active ingredient of Viagra. However, consult your doctor before taking both the drugs together.
Q. Does amlodipine cause gout or coughing?
Amlodipine does not cause gout, in fact it can be taken by gout patients for the appropriate indication. Coughing is a very rare side effect of amlodipine.
Q. What is Eslo 2.5 or Amlopres-5 used for?
Eslo 2.5 or Amlopres-5 are some of the trade names of amlodipine and used for the same indications as amlodipine.


Q. Hydrochlorothiazide is a diuretic,which increases the excretion of urine?
Patients should follow the advice of the doctor regarding its use.
Q. Is hydrochlorothiazide a statin/ opiate?
No.It is the derivative of chlorothiazide.
Q. Is hydrochlorothiazide bad for your kidneys?
No.Hydrochlorthiazide is a safe drug at prescribed dose by your doctor. Consult your doctor if you have kidney disease and follow the advice of the doctor regarding its use.
Q. Can I take hydrochlorothiazide with lisinopril/ ibuprofen/ synthroid/ aspirin/ potassium/ phentermine/ losartan/ naproxen/ magnesium/ vitamins?
Taking other medicines may alter the effects of hydrochlorothiazide. Always consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required.
Q. Does hydrochlorothiazide cause diabetes/ erectile dysfunction/ weight loss/ gout/ constipation/tinnitus/ potassium loss?
Hydrochlorothiazide causing these side effects is rare or uncommon. However, consult your doctor if you experience any of these side effects.
Q. Does hydrochlorothiazide have sulfa in it?
Yes.Hydrochlorothiazide has sulfa and it is chemically known as 6-chloro- 3, 4-dihydro-2 H-1, 2, 4-benzothiadiazine-7-sulfonamide 1, 1-dioxide.
Q. Does hydrochlorothiazide clean your system?
No.Hydrochlorothiazide reduces extra fluid in the body.


Content on this page was last updated on 17 September, 2014, by Dr. Varun Gupta (MD Pharmacology)