Alprax Z 0.25 mg/3 mg Tablet

Prescription Required


Alprax Z 0.25 mg/3 mg Tablet is used to treat insomnia. It helps to calm the brain by decreasing the abnormal and excessive activity of the nerve cells. It also regulates the sleep cycle and helps the patient to fall asleep quickly.

Alprax Z 0.25 mg/3 mg Tablet should be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor as it has high habit-forming potential. However, take it as advised by your doctor because it is not recommended for long-term use. Inform your doctor if you are suffering from any liver or kidney problems before taking this medicine. You should avoid smoking and alcohol while using this medicine. Regular monitoring of blood sugar levels is required while taking this medicine.

Some common side effects of this medicine include confusion, tiredness, and memory impairment. It may also cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. It may cause weight gain or weight loss depending upon person to person. To prevent weight gain, you can eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly. However, weight loss can be managed by consulting a dietitian who can help you in increasing your food portions.

Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Uses of Alprax Z Tablet

Benefits of Alprax Z Tablet

In Insomnia

Alprax Z 0.25 mg/3 mg Tablet is a combination of two medicines that helps treat insomnia (difficulty falling or staying asleep) in people who have problems related to their sleeping habits. Insomnia may cause you to wake up earlier than usual and you may find it difficult to go back to sleep. It works by slowing down the abnormal activity of nerves in the brain to allow sleep. It also improves the sleep-wake cycle and restores it to normal. This helps you relax, feel calm, and more energetic. It also helps you concentrate better and improves your quality of life.

Side effects of Alprax Z Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Alprax Z

  • Confusion
  • Drowsiness
  • Tiredness
  • Uncoordinated body movements
  • Depression
  • Memory impairment

How to use Alprax Z Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Alprax Z 0.25 mg/3 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Alprax Z Tablet works

Alprax Z 0.25 mg/3 mg Tablet is a combination of two medicines: Alprazolam and melatonin, which helps you sleep. Alprazolam is a benzodiazepine. It works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain and induces sleep. Melatonin is a natural hormone which helps to regulate the sleep-wake cycle.

Safety advice

It is unsafe to consume alcohol with Alprax Z 0.25 mg/3 mg Tablet.
Alprax Z 0.25 mg/3 mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
Alprax Z 0.25 mg/3 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Alprax Z 0.25 mg/3 mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Alprax Z 0.25 mg/3 mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Alprax Z 0.25 mg/3 mg Tablet may not be needed in these patients. Please consult your doctor.
Alprax Z 0.25 mg/3 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Alprax Z 0.25 mg/3 mg Tablet may be needed. Please consult your doctor.
There is very limited experience on use of Alprax Z 0.25 mg/3 mg Tablet in patients with underlying liver disease.

What if you forget to take Alprax Z Tablet?

If you miss a dose of Alprax Z 0.25 mg/3 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate brands

For informational purposes only. Consult a doctor before taking any medicines.
Alprax Z 0.25 mg/3 mg Tablet
1% costlier
Stresnil 0.25 Tablet
Aristo Pharmaceuticals Pvt Ltd
37% costlier

Quick tips

  • Alprax Z 0.25 mg/3 mg Tablet is prescribed for the treatment of insomnia.
  • It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two, feeling it is not helping.
  • Do not stop taking Alprax Z 0.25 mg/3 mg Tablet unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
  • Inform your doctor if you have liver disease.
  • Inform your doctor if you are pregnant or breastfeeding.

Fact Box

Habit Forming
Therapeutic Class

Patient concerns

I don't get sleep in the night
Dr. Pushkar Mani
take Alprax 0.25 mg in night
Since last 2 yrs I am sufferin from insomnia. All though I dont feel any stress and no tension. I hv started taking ALPRAX 0.25 pil pl suggest Hi i m waiting for ur response
Dr. Jyoti Kapoor Madan
Sleep problems are often caused by underlying physical and/ or psychological cause. This requires examination of the patient so that proper treatment can be initiated. Often stress/ anxiety/ depression or mood disorder needs to be dealt with and sleeping pills are not adequate treatment. Please go through the link below -
Do you have any questions related to Alprax Z 0.25 mg/3 mg Tablet ?

User feedback


Q. What are the instructions for the storage and disposal of Alprax Z 0.25 mg/3 mg Tablet?

Keep Alprax Z 0.25 mg/3 mg Tablet in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. In which conditions is the use of Alprax Z 0.25 mg/3 mg Tablet contraindicated?

The use of Alprax Z 0.25 mg/3 mg Tablet is considered to be harmful for patients with known allergy to alprazolam or melatonin. Its use should also be avoided in patients with myasthenia gravis, any breathing difficulties or chest diseases, liver diseases and sleep apnea.

Q. Can the use of Alprax Z 0.25 mg/3 mg Tablet cause dependence?

Alprax Z 0.25 mg/3 mg Tablet contains alprazolam which can make you dependent on the medicine. Dependence can lead to withdrawal symptoms when you stop the treatment abruptly. This mainly happens if you have been taking high doses or have been using it for a very long time. Withdrawal symptoms can include a headache, muscle pain, anxiety, restlessness, confusion, mood changes, difficulty in sleeping, irritability, nausea, vomiting, stomach upset and many others.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


  1. Melatonin. Barcarena, Portugal: Iberfar - Indústria Farmacêutica S.A.; 2018 [Accessed 26 Apr. 2019] (online) Available from:External Link
  2. MedIndia. Alprazolam+Melatonin. [Accessed 22 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Country of origin: India

We do not facilitate sale of this product at present


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