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Composition for ALDACTONE

Spironolactone(50 mg)

food interaction for ALDACTONE

alcohol interaction for ALDACTONE

pregnancy interaction for ALDACTONE

lactation interaction for ALDACTONE

It is better to take Aldactone 50 mg tablet with food.
Spironolactone and alcohol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.
Aldactone 50 mg tablet may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Aldactone 50 mg tablet is probably safe to use during breastfeeding. Please consult your doctor.


Spironolactone(50 mg)


Aldactone 50 mg tablet is used in the treatment of hyperaldosteronism (the body produces too much aldosterone, a naturally occurring hormone); low potassium levels; heart failure; and in patients with edema (fluid retention) caused by various conditions, including liver, or kidney disease. It is also used alone or with other medications to treat high blood pressure.

How it works

Aldactone 50 mg tablet belongs to a class of medications called aldosterone receptor antagonists. It causes the kidneys to eliminate unneeded water and sodium from the body into the urine, but reduces the loss of potassium from the body.

Common side effects

Abdominal pain, Abnormal vaginal bleeding, Bloody diarrhea, Breast tenderness, Breast enlargement, Dizziness, Drowsiness, Dry mouth, Fatigue, Headache, Hoarseness of voice, Increased hair growth, Impotence, Restlessness, Unsteadiness, Bloating, Vomiting, Absence of menstrual periods, Irregular menstrual cycle, Excessive thirst


No substitutes found

Expert advice for ALDACTONE

The medicine  can make you feel dizzy or sleepy. Avoid driving or operating machinery until you know how the medicine affects you.
Do not use supplements or salt substitutes that are high in potasium. Consult your doctor if you develop any muscle weakness, skin changes, red or black tarry stool. Avoid taking alcohol with this medication as it may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position.
Do not start or continue spironolactone and consult your doctor:
  • If you have kidney disease, Addison’s disease (an adrenal gland disorder), liver disease, heart disease.
  • If you have high levels of potassium in your blood (hyperkalemia).
  • if you are also taking eplerenone or other potassium sparing diuretics.
  • If you have an electrolyte imbalance (such as low levels of magnesium in your blood).
  • if you take an NSAID (nonsteroidal anti-inflammatory drug), cholestyramine, heparin, lithium, heart or blood pressure medication, potassium supplements, steroid medicine, or another diuretic.

Frequently asked questions for ALDACTONE


Q. Is spironolactone an ACE inhibitor/thiazide diuretic/corticosteroid/steroid/ beta blocker?
No, spironolactone belongs to a class of medications called aldosterone receptor antagonists.
Q. Is spironolactone safe?
Spironolactone is safe, if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is spironolactone over the counter drug?
No, it is available as prescription drug.
Q. Is spironolactone used for weight control, birth control, for acne, loss of hair?
No, spironolactone is used in the treatment of failure of heart, resulting in fluid build-up in lungs or other body tissue (congestive cardiac failure), chronic liver disease (hepatic cirrhosis) with accumulation of fluid in peritoneum liver (ascites and edema), malignant ascites, nephrotic syndrome, diagnosis and treatment of primary aldosteronism.
Q. What is spironolactone/Dytor plus/Aldactone?
Spironolactone/Dytor plus/Aldactone belongs to a class of medications called aldosterone receptor antagonists.
Q. Can spironolactone/Dytor plus/Aldactone cause cancer, hair loss, depression, insomnia, lower blood pressure, constipation, increase estrogen, weight loss?
Spironolactone/Dytor plus/Aldactone can causes hair loss, increase estrogen constipation. Always consult your doctor about possible side effects.
Q. Can i take spironolactone/Aldactone with ibuprofen/vitamins/ antibiotics/ phentermine/ metformin amoxicillin/ Adderall(amphetamine and dextroamphitamine/ Accutane (isotretinoin)/ Benadryl (diphenhydramine)/ Tylenol (acetaminophen)/ Lasix (furosemide)?
Indometacin may increase the diuretic effect of spironolactone. Patients should follow doctors advice regarding its use.
Q. Does spironolactone affect birth control?
No, Always consult your doctor about possible effects.


Content on this page was last updated on 22 March, 2014, by Dr. Varun Gupta (MD Pharmacology)