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09 Dec 2019 | 05:21 PM (IST)
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Akynzeo 300mg/0.5mg Capsule

Prescription Required
Store at room temperature (10-30°C)


Akynzeo 300mg/0.5mg Capsule is a prescription medicine that is used to treat nausea and vomiting due to chemotherapy. It works by blocking the release of chemicals such as serotonin and substance P which are responsible for causing nausea and vomiting.

Akynzeo 300mg/0.5mg Capsule may be taken with or without food. It should be used in the dose and duration as prescribed by your doctor. It is advised to take this medicine at a fixed time.

This medicine should not be taken more than the recommended dose. If you miss any dose, please consult your doctor. It is advised to complete the treatment without any interruption. If you experience any allergic reactions such as skin rash, swelling, and itching, stop the medicine and please consult your doctor.

This medicine is usually well tolerated by patients. The common side effects of this medicine include fatigue, erythema, weakness, headache, constipation, and indigestion. If any of these side effects worsen with time, please consult your doctor.

Inform your doctor if you are pregnant or breastfeeding. This medicine is not safe to use in patients of liver and kidney diseases. Inform your doctor if you are suffering from any disease or are taking any medicines. It is strictly advised not to drive or operate heavy machinery while you are on the treatment as this medicine may make you feel sleepy or dizzy.

Uses of Akynzeo Capsule

  • Nausea and vomiting due to chemotherapy

Side effects of Akynzeo Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Akynzeo

  • Fatigue
  • Erythema (skin redness)
  • Weakness
  • Headache
  • Constipation
  • Indigestion

How to use Akynzeo Capsule

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Akynzeo 300mg/0.5mg Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Akynzeo Capsule works

Akynzeo 300mg/0.5mg Capsule is a combination of two medicines: Netupitant and Palonosetron. These medicines work by blocking the release of chemicals (serotonin and substance P) which cause nausea and vomiting due to chemotherapy. They help prevent nausea and vomiting during both the acute and delayed phase after cancer chemotherapy.

Safety Advice

It is not known whether it is safe to consume alcohol with Akynzeo 300mg/0.5mg Capsule. Please consult your doctor.
Akynzeo 300mg/0.5mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Information regarding the use of Akynzeo 300mg/0.5mg Capsule during breastfeeding is not available. Please consult your doctor.
Akynzeo 300mg/0.5mg Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Akynzeo 300mg/0.5mg Capsule is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.
Akynzeo 300mg/0.5mg Capsule is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Fact Box

Habit Forming

Patient Concerns

Dr. Sunil Sekhri
Tab Domstal 1 tab Stat and keep yourself warm
Vomiting, nausea neck pain backside
Dr. Vijay Verma
Neck pain may be due to nausea NAD vomiting Visit physician for the same
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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


  1. Medscape. Netupitant + Palonosetron. [Accessed 23 Apr. 2019] (online) Available from:External Link
  2. Palonosetron hydrochloride + netupitant. London, UK: Chugai Pharma UK Limited; 2015 [revised 21 Sep. 2017]. [Accessed 23 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
Expires on or after: January, 2021

A licensed vendor partner from your nearest location will deliver Akynzeo 300mg/0.5mg Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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