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18 Feb 2020 | 05:26 PM (IST)
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Abitate 250mg Powder for Injection

Prescription Required

Overview

Introduction

Abitate 250mg Powder for Injection is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.

Abitate 250mg Powder for Injection is given as an injection under the supervision of a doctor, do not self administer the injection. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include vomiting, decreased potassium level in blood, edema (swelling), decreased white blood cell count, fatigue and increased liver enzymes. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.  Other than this, yellowing of skin, loss of appetite, shortness of breath, dark urine and nausea can happen, which indicate some liver problem. Your doctor might check you for liver function, blood pressure, and the level of potassium in your blood.

Before taking it, tell your doctor if have high blood pressure, heart problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.  You may be asked for regular monitoring of blood glucose level while on treatment.

Uses of Abitate Powder for Injection

Side effects of Abitate Powder for Injection

Common
  • Edema (swelling)
  • Vomiting
  • Decreased potassium level in blood
  • Edema (swelling)
  • Decreased white blood cell count
  • Fatigue
  • Increased liver enzymes
  • Anemia (low number of red blood cells)
  • Urinary tract infection
  • Diarrhea
  • High blood pressure
  • Cough
  • Hypercholesterolemia (high cholesterol)
  • Joint swelling
  • Increased levels of blood fat
  • Altered blood sugar level

How to use Abitate Powder for Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Abitate Powder for Injection works

Abitate 250mg Powder for Injection is an anticancer medication. It works by preventing androgen (male hormone) production in man. This is done by inhibiting an enzyme (CYP17) that is responsible for the production of androgen. This is how it slows down the growth of prostate cancer.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Abitate 250mg Powder for Injection. Please consult your doctor.
Pregnancy
UNSAFE
Abitate 250mg Powder for Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breastfeeding
UNSAFE
Abitate 250mg Powder for Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
SAFE
Abitate 250mg Powder for Injection does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Abitate 250mg Powder for Injection is safe to use in patients with kidney disease. No dose adjustment of Abitate 250mg Powder for Injection is recommended.
Because of the limited information, cautious use of Abitate 250mg Powder for Injection is recommended in patients with severe kidney disease.
Liver
CAUTION
Abitate 250mg Powder for Injection should be used with caution in patients with liver disease. Dose adjustment of Abitate 250mg Powder for Injection may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Quick Tips

  • Abitate 250mg Powder for Injection treats prostate cancer that has spread to other parts of the body.
  • It is usually taken with another medicine called prednisolone to reduce unwanted side effects.
  • It must be taken on an empty stomach. Don't eat any food for at least 2 hours before or 1 hour after your dose.
  • Always use effective birth control measures to prevent pregnancy while taking this medicine.
  • Your doctor may regularly monitor your liver function, blood pressure, and the level of potassium in your blood while you are having treatment with this medicine.

Patient Concerns

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I have problem of frequent urination at night. My father had same at his time.Doctor told me that I am having BPH.Also I went through PSA whose result is 1.8 increased prostate gland size is 40 which came in ultrasound report .When doctor did some test by inserting his finger in my rectal area I felt abnormal pain.doctor asked me to go for a culture test so as to check which can be the best medicine for BPH for me. Kindly suggest if it can be something else like prostate cancer.
Dr. Vijay Sharnangat
Medical Oncology and Hematology
May not be prostate cancer, it is only begnin enlargement of prostate.
Do i have prostrate cancer. Married but now having difficulty in having relation with wife. Penis not hard in the morning. Having problem with self spontaneous erection. Please help. God Bless.
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
Not a symptom of prostate cancer
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FAQs

Q. Can Abitate cure prostate cancer?

Abitate does not cure cancer but helps in prolonging and improving the life of the patient. Moreover, when prostate cancer is treated with Abitate then the frequency of fractures is relatively less. Similarly, the increase in pain is less common with Abitate.

Q. Is Abitate a chemotherapy drug?

Abitate is a hormonal treatment not a chemotherapy drug. It is used to treat prostate cancer in adult men that has spread to other parts of the body. Abitate stops your body from making testosterone. This can slow down the growth of prostate cancer.

Q. Why do I need to take prednisolone with Abitate?

Your doctor will always prescribe prednisolone with Abitate. Taking these two medicines together lowers the risk of getting high blood pressure, fluid retention (having too much water in your body), or having reduced levels of potassium in your blood, which can occur due to Abitate.

Q. Does Abitate affect liver?

Abitate can cause severe liver problems. In very rare cases, Abitate may even cause failure of the liver to function (called acute liver failure), which can even lead to death. Tell your doctor if you experience yellowing of the skin or eyes, darkening of the urine, or severe nausea or vomiting, as these could be signs or symptoms of liver problems.

Q. How frequently should the liver investigations be done?

Liver enzymes should be measured prior to starting the treatment, every two weeks for the first three months into the treatment, and monthly thereafter. If you develop clinical symptoms or signs suggestive of liver toxicity, liver enzymes should be measured immediately. If the liver enzyme levels are increased beyond certain levels, your doctor may temporarily discontinue the treatment with Abitate.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 4-5.
  2. Chemocare. Abiraterone Acetate. [Accessed 03 Jul. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
463, 4 th Floor, RPG HOUSE, Dr. Annie Besant Road, Worli, Mumbai – 400 030. Maharashtra, INDIA
A licensed vendor partner from your nearest location will deliver Abitate 250mg Powder for Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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₹76000
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1 Powder for Injection in 1 vial
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