Sulphadiazine 500mg Tablet

Sulfadiazine (500mg)

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Sulphadiazine 500mg Tablet is an antibiotic medicine used to treat bacterial infections in your body. It is effective in infections of the lungs (eg. pneumonia, bronchitis), ear, urinary tract, and intestines. It is also used to treat some parasitic infections.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 17 Dec 2025 | 04:35 PM (IST)

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General Information

Contains

Sulfadiazine (500mg)

Marketer

Abbott

Storage

Store below 30°C

The content is shown in English

Product introduction

Sulphadiazine 500mg Tablet works by stopping the growth of bacteria. It may be taken with or without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. The dose will depend on what you are being treated for, but you should always complete a full course of this antibiotic as prescribed by your doctor. Do not stop taking it until you have finished, even when you feel better. If you stop taking it early, some bacteria may survive and the infection may come back.

The most common side effects of this medicine include nausea, vomiting, diarrhea, and allergic reaction. Seek emergency medical help if you get a rash, itchy skin, swelling of face and mouth, or have difficulty breathing.

Before using it, you should tell your doctor if you are allergic to any antibiotics (especially sulpha medicines) or have any kidney or liver problems. You should also let your doctor know all other medicines you are taking as they may affect, or be affected by this medicine. Pregnant and breastfeeding mothers should consult their doctor before taking this medicine. Your doctor may monitor you with regular blood and urine tests during treatment.

Uses of Sulphadiazine Tablet

Bacterial infections

Benefits of Sulphadiazine Tablet

Bacterial infections
Sulphadiazine 500mg Tablet is an antibiotic medicine which can be used to treat many different infections caused by bacteria. These include infections of the ear, nose, throat, lungs, skin, and eye in adults and children. It is also used for treating typhoid fever and some sexually transmitted diseases like gonorrhea. It works by stopping the growth of the bacteria causing the infection.
This medicine usually makes you feel better quite quickly. However, you should continue taking it as long as it is prescribed even when you feel better, to make sure that all bacteria are killed and do not become resistant.

Side effects of Sulphadiazine Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sulphadiazine

Nausea
Vomiting
Diarrhea
Allergic reaction

How to use Sulphadiazine Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sulphadiazine 500mg Tablet may be taken with or without food.

How Sulphadiazine Tablet works

Sulphadiazine 500mg Tablet is an antibiotic. It stops the bacteria from producing folic acid, a nutrient required for bacterial multiplication.

Quick tips

Your doctor has prescribed Sulphadiazine 500mg Tablet to cure your infection and improve your symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
Your doctor will ensure that you are well hydrated during treatment with this medicine.
Your doctor may get regular blood, urine tests while you are on this medication.
Do not take Sulphadiazine 500mg Tablet if you are pregnant or breastfeeding.
Discontinue Sulphadiazine 500mg Tablet and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.

Safety advice

Alcohol

SAFE

Consuming alcohol with Sulphadiazine 500mg Tablet does not usually cause any harmful side effects.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Sulphadiazine 500mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Sulphadiazine 500mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

SAFE

Sulphadiazine 500mg Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Sulphadiazine 500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Sulphadiazine 500mg Tablet is not recommended in patients with severe kidney disease.

Liver

CAUTION

Sulphadiazine 500mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Sulphadiazine 500mg Tablet is not recommended in patients with severe liver disease.

Interaction with drugs

Taking Sulphadiazine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Cholera Vaccine (Inactivated) (Oral Route)

Do not consume Cholera Vaccine (Inactivated) two weeks before and at least 10 days after consuming Sulfadiazine. Please consult your doctor. Sulfadiazine may reduce the efficacy of Cholera Vaccine (Inactivated).

Severe

Pyrimethamine (Oral Route)

Caution is advised when taking Pyrimethamine with Sulfadiazine. If concurrent use is essential, your doctor may monitor the effects of the medicines and adjust the doses as per the observations.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Severe

Warfarin (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Frequently asked questions

What if I don't get better after using Sulphadiazine 500mg Tablet?

Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.

Can I stop taking Sulphadiazine 500mg Tablet when my symptoms are relieved?

No, do not stop taking Sulphadiazine 500mg Tablet and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.

Fact Box

Chemical Class

Aminobenzenesulfonamides

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Sulphonamides

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

Petri WA Jr. Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1466.
Chambers HF, Deck DH. Sulfonamides, Trimethoprim, & Quinolons. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 817.
ScienceDirect. Sulfadiazine. [Accessed 31 Mar. 2019] (online) Available from:
Sulfadiazine. Ash Road North Wrexham: Wockhardt UK Ltd.; 2008 [revised 28 oct. 2015]. [Accessed 31 Mar. 2019] (online) Available from:

User feedback

Patients taking Sulphadiazine 500mg Tablet

Twice A Day

100%

What are you using Sulphadiazine Tablet for?

Bacterial infections

75%

Others

25%

How much was the improvement?

Excellent

100%

What were the side-effects while using Sulphadiazine 500mg Tablet?

No Side Effect

100%

How do you take Sulphadiazine Tablet?

With food

100%

Please rate Sulphadiazine 500mg Tablet on price

Not Expensive

50%

Expensive

33%

Average

17%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Abbott
Address: 16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Sulphadiazine 500mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Sulphadiazine Tablet

Benefits of Sulphadiazine Tablet

Side effects of Sulphadiazine Tablet

How to use Sulphadiazine Tablet

How Sulphadiazine Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Cholera Vaccine (Inactivated) (Oral Route)

Pyrimethamine (Oral Route)

Methotrexate (Injection Route)

Warfarin (Oral Route)

Methotrexate (Injection Route)

Frequently asked questions

What if I don't get better after using Sulphadiazine 500mg Tablet?

Can I stop taking Sulphadiazine 500mg Tablet when my symptoms are relieved?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

User feedback

Patients taking Sulphadiazine 500mg Tablet

What are you using Sulphadiazine Tablet for?

How much was the improvement?

What were the side-effects while using Sulphadiazine 500mg Tablet?

How do you take Sulphadiazine Tablet?

Please rate Sulphadiazine 500mg Tablet on price

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Disclaimer

Marketer details

Vendor Details

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