Acromegaly

Description of Acromegaly

Definition
 
Acromegaly is a disorder that causes enlargement of hands and feet due to excessive presence of growth hormones
 
Signs and Symptoms 
 
Common symptoms are, 
1. Doughy-feeling skin over the face and extremities
2. Thick and hard nails
3. Deepening of creases on the forehead and nasolabial folds
4. Noticeably large pores
5. Thick and edematous eyelids
6. Enlargement of the lower lip and nose (the nose takes on a triangular configuration)
7. Wide spacing of the teeth and prognathism
8. Cutis verticis gyrata (ie, furrows resembling gyri of the scalp) 
9. Small sessile and pedunculated fibromas (ie, skin tags)
10. Hypertrichosis
11. Oily skin (acne is not common)
12. Hyperpigmentation (40% of patients)
 
Complications and When Should You See a Doctor 
 
Complications may include,
1. Severe headache
2. Arthritis and carpel tunnel syndrome 
3. Enlarged heart 
4. Hypertension
5. Diabetes mellitus
6. Heart failure
7. Kidney Failure 
 
Investigations 

1.You may be recommended to get the levels of the following hormones/substances checked, 
a) Oral glucose level
b) GH levels 
c) IGF-1 levels
 
2.Imaging studies such as, 
a) MRI scan 
b) CT scan 
c) Radiography
 
Content Details
Last updated on:
01 Nov 2021 | 04:56 PM (IST)
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