{"id":7910,"date":"2016-04-13T15:56:16","date_gmt":"2016-04-13T10:26:16","guid":{"rendered":"http:\/\/articles.1mg.com\/?p=7910"},"modified":"2026-05-21T12:25:23","modified_gmt":"2026-05-21T06:55:23","slug":"important-drug-alert-for-diabetics-2","status":"publish","type":"post","link":"https:\/\/www.1mg.com\/articles\/important-drug-alert-for-diabetics-2\/","title":{"rendered":"Important Drug Alert For Diabetics!"},"content":{"rendered":"

\"Drug<\/p>\n

The U.S. Food and Drug Administration (FDA) safety review has recently issued warnings for a commonly used drug for type 2 diabetes. If you are anyone in your family is taking anti-diabetes medications, please read the drug alert carefully.<\/p>\n

1 . What Is The Warning?<\/strong><\/p>\n

According to the warning, diabetes medicines containing\u00a0saxagliptin<\/strong> may increase the risk of heart failure, particularly in patients who already have heart or kidney disease.<\/p>\n

2 . What Is Saxagliptin?\u00a0<\/strong>( Common brand names: Kombiglyze, Onglyza)<\/strong><\/p>\n

-Saxagliptin belongs to the\u00a0the class of dipeptidyl peptidase-4 (DPP-4) inhibitor drugs, which are used along with diet and exercise to lower blood sugar in adults with type 2 diabetes.<\/p>\n

-Saxagliptin acts by inhibiting the enzyme (dipeptidyl peptidase-4 (DPP-4)) which prevents the breakdown of substances called as incretins, ultimately increasing the production of insulin that reduces blood glucose level at fasting and after intake of food.<\/p>\n

-Saxagliptin is available as single-ingredient product or in combination with other diabetes medications such as metformin.<\/p>\n

3 . What Should The Patients Taking These Medicines Do?<\/strong><\/p>\n

-Patients should not stop taking their medicine without first talking to their doctor.<\/p>\n

-Patients who have a pre-existing heart or kidney disease should immediately consult their doctor .<\/p>\n

-Patients who do not have any pre existing heart and kidney problems should also seek their doctor’s opinion regarding the use of this medicine.<\/p>\n

-Patients should immediately contact their doctor if they develop signs and symptoms of heart failure such as:<\/p>\n

-Unusual shortness of breath during daily activities<\/p>\n

-Trouble breathing when lying down<\/p>\n

-Tiredness, weakness, or fatigue<\/p>\n

-Weight gain with swelling in the ankles, feet, legs, or abdomen<\/p>\n","protected":false},"excerpt":{"rendered":"

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