{"id":172140,"date":"2026-03-03T18:57:46","date_gmt":"2026-03-03T13:27:46","guid":{"rendered":"https:\/\/www.1mg.com\/articles\/?p=172140"},"modified":"2026-03-06T13:27:19","modified_gmt":"2026-03-06T07:57:19","slug":"causes-of-obesity-why-it-happens-and-how-new-medications-are-changing-treatment","status":"publish","type":"post","link":"https:\/\/www.1mg.com\/articles\/causes-of-obesity-why-it-happens-and-how-new-medications-are-changing-treatment\/","title":{"rendered":"Causes of Obesity: Why It Happens and How New Medications Are Changing Treatment"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-172142\" title=\"Causes of Obesity: Why It Happens and How New Medications Are Changing Treatment\" src=\"https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2026\/03\/2508.jpg\" alt=\"causes of obesity\" width=\"1000\" height=\"667\" srcset=\"https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2026\/03\/2508.jpg 1000w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2026\/03\/2508-300x200.jpg 300w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2026\/03\/2508-768x512.jpg 768w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2026\/03\/2508-150x100.jpg 150w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><\/p>\n<p><span style=\"font-weight: 400\">Did you know that obesity is now considered a chronic disease [1], not just a lifestyle problem? Every day, millions of people silently carry not just excess weight, but also shame, judgment, and guilt. They are told to \u201cjust eat less\u201d or \u201cmove more&#8221;, but the causes of obesity and what really works are not that simple.\u00a0<\/span><\/p>\n<p><b>Dr. Sarthak Chakarvarthy, Consultant Physician at TATA 1mg, states that \u201cDoctors are treating obesity as a medical condition that sometimes needs medical treatment. Emerging anti-obesity drugs can offer hope.\u201d<\/b><span style=\"font-weight: 400\">\u00a0<\/span><\/p>\n<p><b>This World Obesity Day<\/b><span style=\"font-weight: 400\">, it\u2019s important to pause and look at \u201c8 billion reasons to act on obesity\u201d, which is the theme for this year [2]. The message is simple yet powerful \u2014 with the world\u2019s population now crossing 8 billion, every single life matters. Obesity affects people across age groups, geographies, and income levels. Acting on obesity is not just about individual health \u2014 it is about protecting global health. Because for many people, it isn\u2019t about laziness or lack of willpower. It\u2019s biology, hormones, genetics, and environment. Let\u2019s understand more.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">Obesity Is More Than A Number On the Scale<\/span><\/h2>\n<p><span style=\"font-weight: 400\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-153880\" src=\"https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/09\/shutterstock_2631833459.jpg\" alt=\"Obesity\" width=\"1000\" height=\"667\" srcset=\"https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/09\/shutterstock_2631833459.jpg 1000w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/09\/shutterstock_2631833459-300x200.jpg 300w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/09\/shutterstock_2631833459-768x512.jpg 768w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/09\/shutterstock_2631833459-150x100.jpg 150w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/>According to the World Health Organization (WHO), obesity is defined as abnormal or excessive fat accumulation that presents a health risk [1]. It is classified as a chronic, complex disease influenced by genetic, metabolic, behavioural, and environmental factors.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Obesity is defined using Body Mass Index (BMI), but health risks go far beyond a calculation. Excess body fat, mainly around the abdomen, increases the risk of [3]:<\/span><\/p>\n<p><span style=\"font-weight: 400\">&#8211; Type 2 diabetes<br \/>\n<\/span><span style=\"font-weight: 400\">&#8211; Heart disease<br \/>\n<\/span><span style=\"font-weight: 400\">&#8211; High blood pressure<br \/>\n<\/span><span style=\"font-weight: 400\">&#8211; Fatty liver disease<br \/>\n<\/span><span style=\"font-weight: 400\">&#8211; Joint problems (gout or osteoarthritis)<br \/>\n<\/span><span style=\"font-weight: 400\">&#8211; Sleep apnea<br \/>\n<\/span><span style=\"font-weight: 400\">&#8211; Certain cancers<\/span><\/p>\n<p><span style=\"font-weight: 400\">But what is often overlooked is the emotional toll, anxiety, low self-esteem, social stigma, and constant dieting cycles. Obesity affects physical and mental health together. This increases the chances of developing depression, eating disorders, and similar conditions.<br \/>\n<\/span><a href=\"https:\/\/www.1mg.com\/articles\/5-signs-that-indicate-you-may-be-having-an-eating-disorder\/\" target=\"_blank\" rel=\"noopener\"><b>Read the signs of eating disorders beforehand and stay alert!<\/b><\/a><\/p>\n<p><span style=\"font-weight: 400\">The theme \u201c8 Billion Reasons to Act\u201d highlights that obesity is not a niche problem\u2014it affects families, healthcare systems, and economies worldwide. With over 8 billion people on the planet, rising obesity rates increase the burden of other health issues. Acting early means reducing preventable disease and protecting millions of lives.\u00a0<\/span><\/p>\n<h2><span style=\"font-weight: 400\">Understanding BMI: Where Do You Fall?<\/span><\/h2>\n<p><span style=\"font-weight: 400\">Body Mass Index (BMI) is a screening tool used to classify weight status.\u00a0<\/span><\/p>\n<p><b>Standard World Health Organization (WHO) classifications are [4]:<\/b><\/p>\n<p><span style=\"font-weight: 400\">&#8211; Normal weight: 18.5 \u2013 24.9 kg\/m\u00b2<br \/>\n<\/span><span style=\"font-weight: 400\">&#8211; Overweight: 25 \u2013 29.9 kg\/m\u00b2<br \/>\n<\/span><span style=\"font-weight: 400\">&#8211; Obese: 30 kg\/m\u00b2 and above<\/span><\/p>\n<p><b>Asian\/Indian Cut-offs (More Sensitive to Risk) [4]:<\/b><\/p>\n<p><span style=\"font-weight: 400\">&#8211; Normal weight: 18.5 \u2013 22.9 kg\/m\u00b2<br \/>\n<\/span><span style=\"font-weight: 400\">&#8211; Overweight: 23 \u2013 24.9 kg\/m\u00b2<br \/>\n<\/span><span style=\"font-weight: 400\">&#8211; Obese: 25 kg\/m\u00b2 and above<\/span><\/p>\n<p><span style=\"font-weight: 400\">For Indian populations, health risks like diabetes and heart disease may begin at lower BMI levels. That\u2019s why doctors often use the Asian cut-offs. However, BMI does not measure body fat distribution. Waist circumference and metabolic markers are equally important.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">What Are Some Common Causes of Obesity<\/span><\/h2>\n<p><span style=\"font-weight: 400\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-148110\" src=\"https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/09\/9481.jpg\" alt=\"heart health\" width=\"1000\" height=\"667\" srcset=\"https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/09\/9481.jpg 1000w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/09\/9481-300x200.jpg 300w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/09\/9481-768x512.jpg 768w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/09\/9481-150x100.jpg 150w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/>Obesity develops from multiple overlapping factors \u2014 not just overeating.<\/span><\/p>\n<p><b style=\"font-family: inherit;font-style: inherit\">1. Genetic Predisposition<br \/>\n<\/b><span style=\"font-weight: 400\">Some individuals are biologically more prone to weight gain and fat storage.<\/span><\/p>\n<p><b style=\"font-family: inherit;font-style: inherit\">2. Sedentary Lifestyle<br \/>\n<\/b><span style=\"font-weight: 400\">Long work hours, screen time, and reduced physical movement can significantly lower calorie expenditure.<\/span><\/p>\n<p><b>3. Ultra-Processed Diets<br \/>\n<\/b><span style=\"font-weight: 400\">High intake of refined carbs, sugary beverages, fried snacks, and packaged foods contributes to excess calorie intake.<\/span><\/p>\n<p><b>4. Poor Sleep<br \/>\n<\/b><span style=\"font-weight: 400\">Chronic sleep deprivation can increase hunger hormones and reduce satiety signals.<\/span><\/p>\n<p><b>5. Hormonal Imbalances<br \/>\n<\/b><span style=\"font-weight: 400\">Conditions such as hypothyroidism, PCOS, and insulin resistance can influence weight.<\/span><\/p>\n<p><b style=\"font-family: inherit;font-style: inherit\">6. Stress<br \/>\n<\/b><span style=\"font-weight: 400\">Chronic stress elevates cortisol, which may promote abdominal fat accumulation.<\/span><\/p>\n<p><b>7. Environmental and Social Factors<br \/>\n<\/b><span style=\"font-weight: 400\">Easy access to calorie-dense food and limited access to safe spaces for physical activity also play a role.<\/span><\/p>\n<h3><span style=\"font-weight: 400\">What Should You Do If You\u2019re Struggling With Weight?<\/span><\/h3>\n<p><span style=\"font-weight: 400\">If you are someone who is struggling with weight, you should:<\/span><\/p>\n<p><span style=\"font-weight: 400\">&#8211; Avoid crash diets<\/span><span style=\"font-weight: 400\"><br \/>\n&#8211; Get your blood sugar, thyroid, and metabolic markers checked<br \/>\n<\/span><span style=\"font-weight: 400\">&#8211; Speak to a doctor if BMI is in the overweight or obese range<br \/>\n<\/span><span style=\"font-weight: 400\">&#8211; Ask whether medication is appropriate \u2014 don\u2019t assume<br \/>\n<\/span><span style=\"font-weight: 400\">&#8211; Focus on long-term health, not just appearance<\/span><\/p>\n<h2><span style=\"font-weight: 400\">The Rise of GLP-1-Based Anti-Obesity Medications<\/span><\/h2>\n<h2><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-157163\" src=\"https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/10\/shutterstock_2631027729.jpg\" alt=\"causes of obesity\" width=\"1000\" height=\"667\" srcset=\"https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/10\/shutterstock_2631027729.jpg 1000w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/10\/shutterstock_2631027729-300x200.jpg 300w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/10\/shutterstock_2631027729-768x512.jpg 768w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/10\/shutterstock_2631027729-150x100.jpg 150w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><\/h2>\n<p><span style=\"font-weight: 400\">In recent years, a class of medications known as GLP-1 receptor agonists, including semaglutide, has changed the conversation. Originally developed for type 2 diabetes, these medications were found to support weight reduction significantly.<\/span><\/p>\n<h3><span style=\"font-weight: 400\">How do they work?<\/span><\/h3>\n<p><span style=\"font-weight: 400\">GLP-1 is a hormone naturally released in the gut after eating. It helps regulate appetite and blood sugar. When used as medication, GLP-1 receptor agonists may [5]:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Reduce hunger signals in the brain<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Increase feelings of fullness<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Slow gastric emptying<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Improve blood sugar control<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">As a result, people tend to eat less \u2014 not by force, but because appetite itself is reduced. Heard about food noise \u2013 it&#8217;s something many patients can relate to. The constant thoughts about eating, strong cravings, and difficulty feeling satisfied. For some, GLP-1 medications quiet that internal struggle.<br \/>\n<\/span><a href=\"https:\/\/www.1mg.com\/articles\/what-is-food-noise-and-how-to-quiet-it-for-better-eating-habits\/\" target=\"_blank\" rel=\"noopener\"><b>If you don&#8217;t know about \u2018Food Noise\u2019, just click to know more.<\/b><\/a><\/p>\n<h2><span style=\"font-weight: 400\">Who Are These GLP-1 Medications For?<\/span><\/h2>\n<p><span style=\"font-weight: 400\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-148161\" src=\"https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/09\/shutterstock_2484912413.jpg\" alt=\"Obesity medicine\" width=\"1000\" height=\"666\" srcset=\"https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/09\/shutterstock_2484912413.jpg 1000w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/09\/shutterstock_2484912413-300x200.jpg 300w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/09\/shutterstock_2484912413-768x511.jpg 768w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/09\/shutterstock_2484912413-150x100.jpg 150w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/>GLP-1-based treatments are not cosmetic tools. They are prescribed for individuals who have a BMI \u2265 30 or BMI \u2265 27 with obesity-related conditions like diabetes, etc. However, regular monitoring is still required, and dosages need to be adjusted gradually. Though lifestyle guidance continues, self-medication or using these drugs without medical supervision can be risky.<\/span><\/p>\n<h3><span style=\"font-weight: 400\">Are They Safe?<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Like all medications, GLP-1 receptor agonists have side effects. Common ones include nausea, vomiting, diarrhea or constipation, and reduced appetite. Most side effects are mild and improve over time. However, they are not suitable for everyone. A thorough medical evaluation is necessary before starting treatment.<br \/>\n<\/span><a href=\"https:\/\/www.1mg.com\/online-doctor-consultation?utm_source=Googlefeed%20&amp;utm_medium=Article&amp;utm_campaign=Expert_consult\" target=\"_blank\" rel=\"noopener\"><b>To start with, speak to a professional guide or doctor today!<\/b><\/a><\/p>\n<p><span style=\"font-weight: 400\">Long-term safety data is still expanding, and doctors weigh benefits versus risks carefully. This is not a trend-driven decision; it\u2019s a clinical one.\u00a0<\/span><\/p>\n<p><b>Dr. Sarthak adds that, although GLP-1-based medications have shown promising results, prevention through diet, movement, and systemic changes remains essential.<\/b><\/p>\n<h2><span style=\"font-weight: 400\">Lifestyle Still Comes First<\/span><\/h2>\n<div id=\"attachment_138803\" style=\"width: 1010px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-138803\" class=\"size-full wp-image-138803\" src=\"https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/07\/shutterstock_2228321621.jpg\" alt=\"obesity &amp; weight loss\" width=\"1000\" height=\"667\" srcset=\"https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/07\/shutterstock_2228321621.jpg 1000w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/07\/shutterstock_2228321621-300x200.jpg 300w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/07\/shutterstock_2228321621-768x512.jpg 768w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/07\/shutterstock_2228321621-150x100.jpg 150w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><p id=\"caption-attachment-138803\" class=\"wp-caption-text\"><span style=\"font-size: 14px;font-weight: 400\">Before medications are even considered to reduce the causes of obesity, foundational habits can include:\u00a0<\/span><\/p><\/div>\n<p><b>&#8211; Nutrition:<\/b><span style=\"font-weight: 400\"> Balanced meals with adequate protein, fiber, and controlled portions that can improve insulin sensitivity. Reducing ultra-processed foods and sugary drinks can make a measurable difference.<\/span><\/p>\n<p><b>&#8211; Movement: <\/b><span style=\"font-weight: 400\">Regular physical activity, especially strength training combined with moderate cardio, can support metabolic health.<\/span><\/p>\n<p><b>&#8211; Sleep and Stress: <\/b><span style=\"font-weight: 400\">Chronic sleep deprivation and stress can increase cortisol levels and disrupt appetite regulation.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">These lifestyle changes aren\u2019t optional. They remain central to obesity management, but for some people, lifestyle efforts alone are not enough.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">What About Surgery?<\/span><\/h2>\n<p><span style=\"font-weight: 400\">For individuals with severe obesity or obesity with serious complications, bariatric surgery remains an option. It works by altering gut hormones, appetite signals, and nutrient absorption. Surgery and medication are not competing tools \u2014 they are part of a spectrum of medical care. The right choice depends on individual health status.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">The Way Forward: Compassion Over Criticism<\/span><\/h2>\n<p><span style=\"font-weight: 400\">World Obesity Day is not about promoting weight loss fads. It is about awareness and understanding what the causes of obesity are and what you can really do. Obesity deserves medical attention, just like hypertension or diabetes.\u00a0<\/span><\/p>\n<h2><span style=\"font-weight: 400\">FAQs<\/span><\/h2>\n<p><b>Q. What are the causes of obesity in India?<\/b><\/p>\n<p><span style=\"font-weight: 400\">The causes of obesity are:<\/span><\/p>\n<p><span style=\"font-weight: 400\">&#8211; Sedentary lifestyles<br \/>\n<\/span><span style=\"font-weight: 400\">&#8211; High intake of ultra-processed foods<br \/>\n<\/span><span style=\"font-weight: 400\">&#8211; Sugary beverages<br \/>\n<\/span><span style=\"font-weight: 400\">&#8211; Poor sleep<br \/>\n<\/span><span style=\"font-weight: 400\">&#8211; Stress<br \/>\n&#8211;<\/span><span style=\"font-weight: 400\">\u00a0Genetic predisposition<br \/>\n<\/span><span style=\"font-weight: 400\">&#8211; Hormonal conditions like PCOS or hypothyroidism\u00a0<\/span><\/p>\n<p><b>Q. What are some of the risks involved with obesity?<\/b><\/p>\n<p><span style=\"font-weight: 400\">Obesity increases the risk of type 2 diabetes, high blood pressure, heart disease, fatty liver, and certain cancers. It can also develop joint problems or sleep apnea.<\/span><\/p>\n<p><b>Q. Can obesity be reversed?<\/b><\/p>\n<p><span style=\"font-weight: 400\">Yes, weight reduction and metabolic improvement are possible with sustained lifestyle changes, medical support, and, in some cases, medications or surgery. Early intervention works best.<\/span><\/p>\n<p><b>Q. What is the biggest indicator of obesity?<\/b><\/p>\n<p><span style=\"font-weight: 400\">Body Mass Index (BMI) is commonly used, but waist circumference is also an important indicator, especially for abdominal fat.<\/span><\/p>\n<p><b>Q. Which cancers are caused by obesity?<\/b><\/p>\n<p><span style=\"font-weight: 400\">Obesity is linked to a higher risk of breast (postmenopausal), colorectal, endometrial, pancreatic, kidney, and liver cancers [2].<\/span><\/p>\n<p><b>Q. What are the four pillars of good and balanced health?<\/b><\/p>\n<p><span style=\"font-weight: 400\">The four pillars of optimised health are balanced nutrition, regular physical activity, adequate sleep, and stress management.<\/span><\/p>\n<p><b>Q. What weight is considered dangerously obese?<\/b><\/p>\n<p><span style=\"font-weight: 400\">A BMI of 30 or above is considered obese, and 40 or above is classified as severe or morbid obesity. The higher the BMI, the higher the health risks.<\/span><\/p>\n<p><b>Q. What blood tests are done for obesity?<\/b><\/p>\n<p><span style=\"font-weight: 400\">For obesity, doctors may check fasting blood sugar, HbA1c, lipid profile, thyroid function, and liver function. Sometimes insulin levels are also checked for metabolic health. All these tests are usually done or recommended for obesity.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">References<\/span><\/h2>\n<p><span style=\"font-weight: 400\">1. World Health Organization: WHO. Obesity and overweight. <\/span><a href=\"https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/obesity-and-overweight\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400\">https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/obesity-and-overweight<\/span><\/a><span style=\"font-weight: 400\">.\u00a0<\/span><span style=\"font-weight: 400\">Published December 8, 2025.<br \/>\n<\/span><\/p>\n<p>2. <span style=\"font-size: 14px\">May T. World Obesity Day 2026: 8 Billion Reasons to Act on Obesity. <\/span><i style=\"font-family: inherit;font-weight: inherit\">Research Communities by Springer Nature<\/i><span style=\"font-size: 14px\">. <\/span><a style=\"font-size: 14px\" href=\"https:\/\/communities.springernature.com\/posts\/world-obesity-day-2026-8-billion-reasons-to-act-on-obesity\" target=\"_blank\" rel=\"noopener\"><span class=\"url\">https:\/\/communities.springernature.com\/posts\/world-obesity-day-2026-8-billion-reasons-to-act-on-obesity<\/span>.<\/a><span style=\"font-size: 14px\"> Published March 5, 2026.<\/span><\/p>\n<p><span style=\"font-weight: 400\">3. Health Risks of Overweight &amp;amp; Obesity. National Institute of Diabetes and Digestive and Kidney Diseases. <\/span><a href=\"https:\/\/www.niddk.nih.gov\/health-information\/weight-management\/adult-overweight-obesity\/health-risks\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400\">https:\/\/www.niddk.nih.gov\/health-information\/weight-management\/adult-overweight-obesity\/health-risks<\/span><\/a><span style=\"font-weight: 400\">. Published October 7, 2025.<\/span><\/p>\n<p><span style=\"font-weight: 400\">4. Singh S, Sikri G, Garg M. Body Mass Index and Obesity\u202f: Tailoring \u201ccut-off\u201d for an Asian Indian Male Population. <\/span><i><span style=\"font-weight: 400\">Medical Journal Armed Forces India<\/span><\/i><span style=\"font-weight: 400\">. 2008;64(4):350-353. doi:10.1016\/s0377-1237(08)80019-6\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">5. Popoviciu MS, P\u0103duraru L, Yahya G, Metwally K, Cavalu S. Emerging role of GLP-1 agonists in obesity: A Comprehensive review of randomised controlled trials. <\/span><i><span style=\"font-weight: 400\">International Journal of Molecular Sciences<\/span><\/i><span style=\"font-weight: 400\">. 2023;24(13):10449. doi:10.3390\/ijms241310449<\/span><\/p>\n<p><b>(The article is written by Sneha Jajoo, Intern, Clinical Health &amp; Content, and is reviewed by<\/b><a href=\"https:\/\/www.1mg.com\/editorial-policy-processes\/dr.-subita-alagh-120\" target=\"_blank\" rel=\"noopener\"><b>\u00a0Dr.Subita Alagh,\u00a0<\/b><\/a><b>Assistant Team Lead, Disease Content.)\u00a0<\/b><\/p>\n","protected":false},"excerpt":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-172142\" src=\"https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2026\/03\/2508.jpg\" alt=\"causes of obesity\" Title=\"Causes of Obesity: Why It Happens and How New Medications Are Changing Treatment\" width=\"1000\" height=\"667\" srcset=\"https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2026\/03\/2508.jpg 1000w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2026\/03\/2508-300x200.jpg 300w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2026\/03\/2508-768x512.jpg 768w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2026\/03\/2508-150x100.jpg 150w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><\/p>\n","protected":false},"author":103,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27,47],"tags":[488,164,33893],"class_list":["post-172140","post","type-post","status-publish","format-standard","hentry","category-health-a-z","category-weight-loss","tag-health","tag-obesity","tag-obesity-treatment"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.1 - 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