{"id":138675,"date":"2025-07-24T13:25:50","date_gmt":"2025-07-24T07:55:50","guid":{"rendered":"https:\/\/www.1mg.com\/articles\/?p=138675"},"modified":"2025-07-24T13:25:50","modified_gmt":"2025-07-24T07:55:50","slug":"is-obesity-genetic","status":"publish","type":"post","link":"https:\/\/www.1mg.com\/articles\/is-obesity-genetic\/","title":{"rendered":"Is Obesity Genetic?"},"content":{"rendered":"<div id=\"attachment_138678\" style=\"width: 1010px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-138678\" class=\"size-full wp-image-138678\" title=\"Is Obesity Genetic?\" src=\"https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/07\/shutterstock_2456550461.jpg\" alt=\"Obesity-genetics\" width=\"1000\" height=\"621\" srcset=\"https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/07\/shutterstock_2456550461.jpg 1000w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/07\/shutterstock_2456550461-300x186.jpg 300w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/07\/shutterstock_2456550461-768x477.jpg 768w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/07\/shutterstock_2456550461-150x93.jpg 150w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><p id=\"caption-attachment-138678\" class=\"wp-caption-text\">Photo Credit: Shutterstock<\/p><\/div>\n<p><span style=\"font-weight: 400\">When it comes to what causes obesity, there&#8217;s a question that&#8217;s commonly asked: Is obesity genetic? Here, we&#8217;ll take a look at how your genes can influence your weight and how likely you are to develop obesity. We&#8217;ll also look at some of the research findings that support the link between genetics and obesity.\u00a0<\/span><\/p>\n<p><b>If you&#8217;re living with obesity, you&#8217;re not alone \u2014 support is available.<\/b><span style=\"font-weight: 400\"><br \/>\n<\/span><a href=\"https:\/\/www.1mg.com\/survey-form?survey_id=66fb7a6dfc64dbae7b3eea9b&amp;source=content_blog&amp;sku_name=venus\"><b>Connect with an Obesity Counselor<\/b><span style=\"font-weight: 400\"><br \/>\n<\/span><span style=\"font-weight: 400\"><br \/>\n<\/span><\/a><span style=\"font-weight: 400\">It&#8217;s impossible to identify a specific reason why a person gains weight and develops obesity. However, we do know that genetics is one of the possible causes of obesity. Ongoing research on the relationship between genetics and obesity show that genes influence:\u00a0<\/span><\/p>\n<ul>\n<li><span style=\"font-weight: 400\"> How much food you tend to eat while sitting.\u00a0<\/span><\/li>\n<li><span style=\"font-weight: 400\"> How you respond when you feel full.\u00a0<\/span><\/li>\n<li><span style=\"font-weight: 400\"> How much enjoyment you get from certain types of food.\u00a0<\/span><\/li>\n<li><span style=\"font-weight: 400\"> How much energy you need to run basic body functions (such as breathing or circulating blood in your body).\u00a0<\/span><\/li>\n<li><span style=\"font-weight: 400\"> How and where excess calories are stored as fat in your body.\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">Just as genes can determine the colour of your eyes, genes can also determine your tendency to put on weight or develop obesity.\u00a0<\/span><\/p>\n<h2><strong>Genetics and obesity: Where does the environment come in?\u00a0<\/strong><\/h2>\n<p><span style=\"font-weight: 400\">Genes play a central role in obesity. But if genetics and obesity are closely related, why does it seem like more people are affected by obesity now<\/span><i><span style=\"font-weight: 400\">? <\/span><\/i><span style=\"font-weight: 400\">There were very few people with obesity a hundred years ago &#8211; so is obesity really genetic?\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Our genes haven&#8217;t changed much over the last hundred years. In fact, they haven&#8217;t really changed over the past 50,000 years. What has changed is our environment.<\/span><span style=\"font-weight: 400\"><br \/>\n<\/span><span style=\"font-weight: 400\"><br \/>\n<\/span><span style=\"font-weight: 400\">As the geneticist Francis Collins puts it, &#8220;Genetics loads the gun and the environment pulls the trigger.&#8221; That means that genetic factors and environmental factors may not work on their own, but interact with each other to produce a result. <\/span><span style=\"font-weight: 400\"><br \/>\n<\/span><span style=\"font-weight: 400\"><br \/>\n<\/span><span style=\"font-weight: 400\">We now live in a different environment compared to people who lived a hundred or so years ago. We live with different types of stress, food, and technology. The modern world interacts with our genes and obesity is part of the result.<\/span><span style=\"font-weight: 400\"><br \/>\n<\/span><span style=\"font-weight: 400\"><br \/>\n<\/span><span style=\"font-weight: 400\">Think of genetics and obesity as two pots. They are different sizes: one pot holds 5 litres while the other pot holds 50 litres. The pots stand in the rain overnight and in the morning, both pots are full of water.<\/span><span style=\"font-weight: 400\"><br \/>\n<\/span><span style=\"font-weight: 400\"><br \/>\n<\/span><span style=\"font-weight: 400\">When you look at both pots, you can see that the larger pot holds more water than the smaller pot. This is because the bigger pot was made to hold more water. In other words, you need both your genetic make-up (how the pot was made) and the environment (the rain) to develop obesity.<\/span><span style=\"font-weight: 400\"><br \/>\n<\/span><\/p>\n<h2><strong>Research on genetics and obesity<\/strong><\/h2>\n<p><span style=\"font-weight: 400\">Some of the first clues of a link between genetics and obesity came from researchers from the University of Michigan. In 1952, they conducted a study with 81 pairs of twins where they measured the twins in many ways, including foot length, forearm length, and even nose height.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">The measurements enabled the researchers to figure out the likelihood that these different traits were inherited from the twins&#8217; parents. This is called heritability. Out of all the traits that the researchers measured, they found that the ones with the highest heritability rate were body weight and waist circumference. Many studies comparing twins have been done since. Researchers found that whether they were raised together or apart, identical twins were similar in weight.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">This shows that your environment, how you live, and what you do are not the only things that influence your body weight. Instead, genes have a lot of power in determining how much you weigh. Together, these findings provide indisputable evidence that genetics and obesity are closely related. Some evidence suggests obesity is between 40% to 70% determined by genetics. This means that the genes you inherit from your parents may increase your risk of developing obesity.<\/span><span style=\"font-weight: 400\"><br \/>\n<\/span><\/p>\n<h2><strong>Taking genetics and obesity into account\u00a0<\/strong><\/h2>\n<p><span style=\"font-weight: 400\">The more you know about genetics and obesity, the more informed you are when making decisions about managing your weight. For example, you can be more aware of the different triggers in your environment that can make you eat more or increase the risk of developing obesity.<\/span><\/p>\n<p><span style=\"font-weight: 400\">It&#8217;s also worthwhile to consider that because of our individual genetics and obesity factors, we may respond differently to different types of treatment. Strategies and treatments that work for one person may not work for another. That&#8217;s why each person needs an individual approach to managing weight.\u00a0<\/span><\/p>\n<p><b>Have questions about managing weight with medical support? Our expert can help guide you.<\/b> <a href=\"https:\/\/www.1mg.com\/survey-form?survey_id=66fb7a6dfc64dbae7b3eea9b&amp;source=content_blog&amp;sku_name=venus\"><b>Hear from us<\/b><\/a><b>\u00a0<\/b><\/p>\n<p><b>Disclaimer:<\/b><span style=\"font-weight: 400\"> This article is curated in partnership with Novo Nordisk. The information is for educational purposes only and is not a substitute for medical advice. Weight loss medications use should be individualized and should be taken under guidance of a doctor. Please note that Tata 1mg does not endorse any brands and is not responsible for their efficacy.<\/span><\/p>\n<p><b>(The article is written by <\/b><a href=\"https:\/\/www.1mg.com\/editorial-policy-processes\/dr.-nitika-makhija-93\"><b>Dr. Nitika Makhija, Manager, Clinical Health and Content<\/b><\/a> <b>\u00a0and is reviewed by <\/b><a href=\"https:\/\/www.1mg.com\/editorial-policy-processes\/dr.-swati-mishra-12\"><b>Dr. Swati Mishra,Director (Clinical Health &amp; Content<\/b><\/a><span style=\"font-weight: 400\">)<\/span><\/p>\n<h2><strong>References<\/strong><\/h2>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Clark PJ. The heritability of certain anthropometric characters as ascertained from measurements of twins. Am J Hum Cenet 1956; 8:49-54.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Waalen J. The genetics of human obesity. Translational Research 2014; 164(4):293\u2013301.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Guyenet S. The hungry brain. Outsmarting the instincts that make us overeat. New York: Flatiron 2017.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Farooqi IS. Genetics of Obesity. In: Thomas A Wadden &amp; George A Bray (eds.). Handbook of Obesity Treatment. New York: Guilford Press 2018;64-74.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Guyenet SJ &amp; Schwartz MW. Regulation of Food Intake, Energy Balance, and Body Fat Mass: Implications for the Pathogenesis and Treatment of Obesity. The Journal of Clinical Endocrinology &amp; Metabolism 2012; 97:745-755.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Morris R. Stranger in a strange land: an optimal-environments account of evolutionary mismatch. Synthese 2018;1-26.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Qi L &amp; Cho YA. Gene-environment interaction and obesity. Nutr Rev 2008; 66(12):684- 694.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Bell CG, Walley AJ &amp; Proguel P. The genetics of human obesity. Nature Reviews &#8211; Genetics 2005; 6:221-234.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Proietto J. Body Weight Regulation. Essential Knowledge to manage weight and keep it off. Xlibris 2016.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Sahu M, Prasuna JG. Twin studies: A unique epidemiological tool. Indian Journal of Community Medicine. 2016 Jul 1;41(3):177-182.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">McPherson R. Genetic contributors to obesity. Canadian Journal of Cardiology. 2007 Aug 1;23:23A-7A.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">NIH. What causes obesity and overweight? [online]. Available from:https:\/\/www.nichd.nih.gov\/health\/topics\/obesity\/conditioninfo\/causeAccessed on 17th December 2024\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Van der Klaauw AA, Farooqi IS. The hunger genes: pathways to obesity. Cell. 2015 Mar 26;161(1<\/span><b>)<\/b><span style=\"font-weight: 400\">:119-132.\u00a0<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-138678\" src=\"https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/07\/shutterstock_2456550461.jpg\" alt=\"Obesity-genetics\" title=\"Is Obesity Genetic?\" width=\"1000\" height=\"621\" srcset=\"https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/07\/shutterstock_2456550461.jpg 1000w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/07\/shutterstock_2456550461-300x186.jpg 300w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/07\/shutterstock_2456550461-768x477.jpg 768w, https:\/\/www.1mg.com\/articles\/wp-content\/uploads\/2025\/07\/shutterstock_2456550461-150x93.jpg 150w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><\/p>\n","protected":false},"author":73,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27,47],"tags":[164,204],"class_list":["post-138675","post","type-post","status-publish","format-standard","hentry","category-health-a-z","category-weight-loss","tag-obesity","tag-weight-loss"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Is Obesity Genetic? - Tata 1mg Capsules<\/title>\n<meta name=\"description\" content=\"When it comes to what causes obesity, there&#039;s a question that&#039;s commonly asked: Is obesity genetic? 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